Two sample MR report
BTN3A2_T Proliferating against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 28 | 0.0995693 | 0.0433072 | 0.0297834 |
| Weighted median | 28 | 0.0327170 | 0.0049692 | 0.0000000 |
| Inverse variance weighted | 28 | 0.0204087 | 0.0057865 | 0.0004204 |
| Simple mode | 28 | 0.0326563 | 0.0066865 | 0.0000416 |
| Weighted mode | 28 | 0.0328963 | 0.0065651 | 0.0000296 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 65.00572 | 26 | 3.44e-05 |
| Inverse variance weighted | 73.49862 | 27 | 3.50e-06 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0770654 | 0.0418139 | 0.0767502 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003989 | 1e-07 | TRUE | 0.0598364 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
